Multilevel pharmacokinetics-driven modeling of metabolomics data
نویسندگان
چکیده
منابع مشابه
Enhancing Learning from Imbalanced Classes via Data Preprocessing: A Data-Driven Application in Metabolomics Data Mining
This paper presents a data mining application in metabolomics. It aims at building an enhanced machine learning classifier that can be used for diagnosing cachexia syndrome and identifying its involved biomarkers. To achieve this goal, a data-driven analysis is carried out using a public dataset consisting of 1H-NMR metabolite profile. This dataset suffers from the problem of imbalanced classes...
متن کاملmodeling loss data by phase-type distribution
بیمه گران همیشه بابت خسارات بیمه نامه های تحت پوشش خود نگران بوده و روش هایی را جستجو می کنند که بتوانند داده های خسارات گذشته را با هدف اتخاذ یک تصمیم بهینه مدل بندی نمایند. در این پژوهش توزیع های فیزتایپ در مدل بندی داده های خسارات معرفی شده که شامل استنباط آماری مربوطه و استفاده از الگوریتم em در برآورد پارامترهای توزیع است. در پایان امکان استفاده از این توزیع در مدل بندی داده های گروه بندی ...
application of several data-driven techniques for rainfall-runoff modeling
in this study, several data-driven techniques including system identification, adaptive neuro-fuzzy inference system (anfis), artificial neural network (ann) and wavelet-artificial neural network (wavelet-ann) models were applied to model rainfall-runoff (rr) relationship. for this purpose, the daily stream flow time series of hydrometric station of hajighoshan on gorgan river and the daily rai...
متن کاملMultilevel Modeling of Complex Survey Data
We describe a multivariate, multilevel, pseudo maximum likelihood estimation method for multistage stratified cluster sampling designs, including finite population and unequal probability sampling. Multilevel models can be estimated with this method while incorporating the sampling design in the standard error computation. Design based adjustment of the likelihood ratio test (LRT) statistic is ...
متن کاملHierarchical Linear Modeling of Multilevel Data
Most data involving organizations are hierarchical in nature and often contain variables measured at multiple levels of analysis. Hierarchical linear modeling (HLM) is a relatively new and innovative statistical method that organizational scientists have used to alleviate some common problems associated with multilevel data, thus advancing our understanding of organizations. This article presen...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Metabolomics
سال: 2017
ISSN: 1573-3882,1573-3890
DOI: 10.1007/s11306-017-1164-4